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E Santagostino Selected Research

nonacog beta pegol

7/2017Pharmacokinetics of a novel extended half-life glycoPEGylated factor IX, nonacog beta pegol (N9-GP) in previously treated patients with haemophilia B: results from two phase 3 clinical trials.
1/2017Insight into health-related quality of life of young children with haemophilia B treated with long-acting nonacog beta pegol recombinant factor IX.
1/2016Nonacog beta pegol in previously treated children with hemophilia B: results from an international open-label phase 3 trial.

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E Santagostino Research Topics

Disease

49Hemophilia A (Haemophilia)
11/2020 - 01/2000
21Hemorrhage
07/2017 - 01/2000
12Hemophilia B (Haemophilia B)
10/2020 - 10/2004
4Infections
09/2016 - 07/2000
4Afibrinogenemia (Fibrinogen Deficiency)
04/2005 - 02/2000
3Joint Diseases (Joint Disease)
09/2011 - 07/2006
2Chronic Disease (Chronic Diseases)
09/2014 - 05/2012
2von Willebrand Diseases (von Willebrand's Disease)
05/2012 - 05/2012
2Inherited Blood Coagulation Disorders
05/2012 - 01/2000
2Body Weight (Weight, Body)
10/2004 - 07/2004
1Anaphylaxis (Anaphylactic Shock)
07/2017
1Hypersensitivity (Allergy)
07/2017
1Chronic Hepatitis C
09/2016
1Rare Diseases (Rare Disease)
05/2014
1Coinfection
12/2009
1Fibrosis (Cirrhosis)
12/2009
1Liver Diseases (Liver Disease)
12/2009
1Hemarthrosis
02/2006
1Congenital, Hereditary, and Neonatal Diseases and Abnormalities (Congenital Disorders)
04/2005
1Hepatitis C
10/2004
1Arthritis (Polyarthritis)
10/2004
1Hemoperitoneum
10/2001
1Factor V Deficiency
12/2000
1Acquired Immunodeficiency Syndrome (AIDS)
07/2000
1Disease Progression
07/2000

Drug/Important Bio-Agent (IBA)

24Factor VIII (Coagulation Factor VIII)IBA
11/2020 - 10/2001
9Factor IX (Coagulation Factor IX)FDA LinkGeneric
10/2020 - 10/2001
7recombinant factor VIII N8IBA
09/2017 - 09/2013
6recombinant FVIIa (rFVIIa)FDA Link
07/2016 - 10/2001
4AlbuminsIBA
11/2016 - 10/2001
4ThrombinFDA Link
07/2016 - 04/2010
4Blood Coagulation Factors (Coagulation Factor)IBA
05/2012 - 10/2004
4Fibrinogen (Factor I)FDA Link
04/2005 - 02/2000
3nonacog beta pegolIBA
07/2017 - 01/2016
3AntigensIBA
07/2017 - 04/2005
3AntibodiesIBA
07/2017 - 12/2008
3Proteins (Proteins, Gene)FDA Link
11/2016 - 11/2015
3InterferonsIBA
09/2016 - 10/2004
3Messenger RNA (mRNA)IBA
08/2011 - 12/2000
26-pyruvoyltetrahydropterin synthase (PTPS)IBA
10/2020 - 09/2013
2Neutralizing AntibodiesIBA
07/2017 - 03/2014
2Nonsense Codon (Nonsense Mutation)IBA
07/2017 - 12/2001
2Recombinant Fusion ProteinsIBA
11/2016 - 07/2016
2Ribavirin (Virazole)FDA LinkGeneric
09/2016 - 12/2009
2Pharmaceutical PreparationsIBA
07/2016 - 07/2013
2von Willebrand factor drug combination factor VIIIIBA
01/2016 - 01/2013
2IsoantibodiesIBA
09/2013 - 01/2013
2Biological ProductsIBA
08/2011 - 11/2009
2Deamino Arginine Vasopressin (Desmopressin)FDA LinkGeneric
08/2011 - 11/2009
2Factor VIIa (Activated Factor VII)IBA
09/2009 - 10/2001
2Factor VII (Proconvertin)IBA
05/2009 - 07/2004
1Immunoglobulin E (IgE)IBA
07/2017
1Immunoglobulin G (IgG)IBA
07/2017
1Leukotriene C4IBA
07/2017
1human F8 proteinFDA Link
09/2016
1daclatasvirIBA
09/2016
1sugar formulated recombinant FVIIIIBA
01/2015
1Sucrose (Saccharose)IBA
01/2015
1FHDIBA
11/2011
1RNA (Ribonucleic Acid)IBA
12/2009
1Prothrombin (Factor II)IBA
09/2009
1malmo protocolIBA
10/2004
1factor VII clotting antigenIBA
07/2004
1Factor V (Coagulation Factor V)IBA
12/2000
1fibrinopeptides gammaIBA
10/2000
1Chemokine CXCL12IBA
07/2000
1BBeta fibrinogenIBA
02/2000
1fibrinogen AalphaIBA
02/2000

Therapy/Procedure

22Therapeutics
11/2020 - 01/2000
3Injections
07/2016 - 01/2015
2Operative Surgical Procedures
07/2016 - 10/2001
1Polypharmacy
01/2018
1Time-to-Treatment
01/2011
1Intravenous Infusions
01/2010
1Replacement Arthroplasty
07/2006
1Aftercare (After-Treatment)
10/2001
1Minor Surgical Procedures (Minor Surgery)
10/2001